Motif ID: TFAP2{A,C}.p2

Z-value: 1.214


Transcription factors associated with TFAP2{A,C}.p2:

Gene SymbolEntrez IDGene Name
TFAP2A 7020 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C 7022 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
TFAP2Achr6_-_104197860.386.4e-02Click!
TFAP2Cchr20_+_552043070.096.8e-01Click!


Activity profile for motif TFAP2{A,C}.p2.

activity profile for motif TFAP2{A,C}.p2


Sorted Z-values histogram for motif TFAP2{A,C}.p2

Sorted Z-values for motif TFAP2{A,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2{A,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_80679897 4.030 NM_001040708
NM_012258
HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr8_-_48650683 3.552 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr1_-_95007139 2.852 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr4_+_4861371 2.109 NM_002448
MSX1
msh homeobox 1
chr8_-_48650703 2.005 NM_005195
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr1_-_41328002 1.953 NM_133467
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr20_+_55966440 1.894 NM_017495
NM_183425
RBM38

RNA binding motif protein 38

chr4_+_139936938 1.860 NM_012118
CCRN4L
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr6_-_143266283 1.841 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr19_+_45251933 1.764 NM_005178
BCL3
B-cell CLL/lymphoma 3
chr21_-_35987144 1.736 NM_004414
RCAN1
regulator of calcineurin 1
chr9_-_38069082 1.643 SHB
Src homology 2 domain containing adaptor protein B
chr1_-_41328019 1.619 CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr15_+_67358194 1.543 NM_005902
SMAD3
SMAD family member 3
chr9_-_140196702 1.497 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr16_+_29817810 1.449 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr18_+_77155927 1.434 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr20_+_6748744 1.433 NM_001200
BMP2
bone morphogenetic protein 2
chr17_-_73874056 1.426 TRIM47
tripartite motif containing 47
chr11_+_43963809 1.398 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr15_+_67358161 1.389 SMAD3
SMAD family member 3
chr14_-_35873823 1.347 NM_020529
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr20_-_43977023 1.272 NM_002999
SDC4
syndecan 4
chr17_-_73874634 1.257 NM_033452
TRIM47
tripartite motif containing 47
chr15_+_41786055 1.255 NM_002220
ITPKA
inositol-trisphosphate 3-kinase A
chr15_+_81293286 1.228 NM_022566
MESDC1
mesoderm development candidate 1
chr12_-_117319231 1.216 NM_003806
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr6_-_4079390 1.195 NM_173563
C6orf146
chromosome 6 open reading frame 146
chr16_+_29817426 1.187 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr1_+_16010838 1.169 PLEKHM2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr19_+_39897457 1.129 NM_003407
ZFP36
zinc finger protein 36, C3H type, homolog (mouse)
chr2_+_121103670 1.099 NM_002193
INHBB
inhibin, beta B
chr10_+_6186878 1.091 PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr10_+_112257624 1.089 NM_004419
DUSP5
dual specificity phosphatase 5
chr19_-_41859519 1.076 TGFB1
transforming growth factor, beta 1
chr17_+_4402128 1.067 NM_001124758
SPNS2
spinster homolog 2 (Drosophila)
chr10_+_28966419 1.025 NM_012342
BAMBI
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
chr16_+_57406398 1.008 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr14_-_51134862 0.987 SAV1
salvador homolog 1 (Drosophila)
chr16_+_86600856 0.979 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr19_-_41859830 0.972 NM_000660
TGFB1
transforming growth factor, beta 1
chr21_-_35986744 0.949 NM_203417
RCAN1
regulator of calcineurin 1
chr19_+_45504686 0.941 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chrX_-_54521866 0.917 FGD1
FYVE, RhoGEF and PH domain containing 1
chr18_+_77155714 0.901 NM_006162
NM_172388
NM_172390
NFATC1


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1


chr19_-_41858948 0.896 TGFB1
transforming growth factor, beta 1
chr2_+_85360373 0.895 NM_031283
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr10_+_6186758 0.887 NM_001145443
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr11_-_1593149 0.884 NM_004420
DUSP8
dual specificity phosphatase 8
chr10_+_6186903 0.871 PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr12_+_122459791 0.866 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr7_+_129251579 0.860 NRF1
nuclear respiratory factor 1
chr1_+_16010816 0.858 NM_015164
PLEKHM2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr19_-_18391440 0.858


chr2_+_12856813 0.857 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chrX_-_48814758 0.856 OTUD5
OTU domain containing 5
chr19_-_41859253 0.852 TGFB1
transforming growth factor, beta 1
chr5_-_131826426 0.841 NM_002198
IRF1
interferon regulatory factor 1
chr18_+_77155966 0.838 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr19_-_41859332 0.832 TGFB1
transforming growth factor, beta 1
chr11_-_128392061 0.823 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr19_+_3185927 0.817 NCLN
nicalin
chr12_-_121734543 0.812 NM_172226
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr21_+_37507209 0.809 NM_001236
CBR3
carbonyl reductase 3
chr2_-_208489695 0.792 NM_145280
METTL21A
methyltransferase like 21A
chr8_+_61591358 0.791 CHD7
chromodomain helicase DNA binding protein 7
chr5_+_179247841 0.786 NM_003900
SQSTM1
sequestosome 1
chr9_-_95896498 0.773 NM_004148
NINJ1
ninjurin 1
chr11_-_63536112 0.771 NM_001144936
C11orf95
chromosome 11 open reading frame 95
chr19_+_3185965 0.770 NCLN
nicalin
chr16_-_89007605 0.764 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr1_+_37940129 0.762 ZC3H12A
zinc finger CCCH-type containing 12A
chr14_-_51135021 0.757 NM_021818
SAV1
salvador homolog 1 (Drosophila)
chr2_-_235405692 0.756 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr5_+_139027907 0.754 CXXC5
CXXC finger protein 5
chr9_-_38069207 0.752 NM_003028
SHB
Src homology 2 domain containing adaptor protein B
chr17_+_40913233 0.750 RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr5_+_139028483 0.747 CXXC5
CXXC finger protein 5
chr5_+_139027955 0.731 CXXC5
CXXC finger protein 5
chrX_-_54522318 0.722 NM_004463
FGD1
FYVE, RhoGEF and PH domain containing 1
chr1_+_45265896 0.720 PLK3
polo-like kinase 3
chr7_+_155089614 0.719 INSIG1
insulin induced gene 1
chr9_+_139606916 0.717 NM_152421
FAM69B
family with sequence similarity 69, member B
chr3_+_51428698 0.712 NM_013286
RBM15B
RNA binding motif protein 15B
chr16_+_11762235 0.711 NM_003498
SNN
stannin
chr5_+_10564431 0.709 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr22_-_19511777 0.706 CLDN5
claudin 5
chr11_-_78128765 0.705 GAB2
GRB2-associated binding protein 2
chr18_+_77155943 0.703 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr17_+_15848230 0.703 NM_000676
ADORA2B
adenosine A2b receptor
chr17_-_17399494 0.695 NM_001199989
NM_016084
RASD1

RAS, dexamethasone-induced 1

chr19_+_13906207 0.693 NM_023072
ZSWIM4
zinc finger, SWIM-type containing 4
chrX_+_152953751 0.691 NM_001142805
NM_005629
SLC6A8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8

chr1_-_114696471 0.691 NM_001253772
SYT6
synaptotagmin VI
chr6_+_36646455 0.688 NM_000389
NM_001220778
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr5_+_56111379 0.685 MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr16_+_30406711 0.676 NM_152652
ZNF48
zinc finger protein 48
chr2_+_191513832 0.663 NM_005966
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr11_-_65325391 0.660 LTBP3
latent transforming growth factor beta binding protein 3
chr8_+_37654406 0.653 GPR124
G protein-coupled receptor 124
chr18_-_48723689 0.653 MEX3C
mex-3 homolog C (C. elegans)
chr14_-_51135041 0.652 SAV1
salvador homolog 1 (Drosophila)
chr13_-_107187312 0.643 NM_004093
EFNB2
ephrin-B2
chr8_+_81398416 0.638 NM_001105539
NM_023929
ZBTB10

zinc finger and BTB domain containing 10

chr17_-_61777467 0.638 LIMD2
LIM domain containing 2
chr6_+_12012723 0.634 NM_002114
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr8_-_38325524 0.630 FGFR1
fibroblast growth factor receptor 1
chr12_-_121734474 0.629 CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr6_+_135502445 0.629 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr2_-_39348127 0.627 SOS1
son of sevenless homolog 1 (Drosophila)
chr2_+_231577624 0.627 CAB39
calcium binding protein 39
chr19_-_3700466 0.624 NM_001195733
NM_012398
PIP5K1C

phosphatidylinositol-4-phosphate 5-kinase, type I, gamma

chr8_+_126442557 0.621 NM_025195
TRIB1
tribbles homolog 1 (Drosophila)
chr11_+_109964086 0.618 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr19_+_3185860 0.613 NM_020170
NCLN
nicalin
chr7_+_6144589 0.610 USP42
ubiquitin specific peptidase 42
chr5_+_139028025 0.605 NM_016463
CXXC5
CXXC finger protein 5
chr12_-_57400199 0.605 NM_014830
ZBTB39
zinc finger and BTB domain containing 39
chr22_-_19512001 0.604 CLDN5
claudin 5
chr11_-_119234628 0.603 USP2
ubiquitin specific peptidase 2
chr20_-_62462568 0.599 ZBTB46
zinc finger and BTB domain containing 46
chr21_-_28217272 0.596 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr3_-_129325175 0.590 NM_015103
PLXND1
plexin D1
chr4_+_1005609 0.590 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chrX_+_149531439 0.590 NM_001177465
MAMLD1
mastermind-like domain containing 1
chr6_+_135502477 0.583 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr15_+_41221530 0.583 NM_019074
DLL4
delta-like 4 (Drosophila)
chr19_-_3700387 0.582 PIP5K1C
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
chr8_+_37654395 0.581 NM_032777
GPR124
G protein-coupled receptor 124
chr3_+_51428720 0.577 RBM15B
RNA binding motif protein 15B
chr21_-_28217692 0.576 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr3_+_47866474 0.575 DHX30
DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr7_+_155250705 0.575 NM_001427
EN2
engrailed homeobox 2
chr2_+_234263153 0.571 DGKD
diacylglycerol kinase, delta 130kDa
chr8_+_22423170 0.570 NM_001018003
SORBS3
sorbin and SH3 domain containing 3
chr22_+_50354428 0.569 PIM3
pim-3 oncogene
chr19_+_10828772 0.569 DNM2
dynamin 2
chr2_+_231577536 0.566 NM_016289
CAB39
calcium binding protein 39
chr8_+_86089641 0.565


chr16_+_81478774 0.564 NM_198390
CMIP
c-Maf inducing protein
chr4_+_103422730 0.562 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr1_+_52608045 0.561 NM_004799
NM_007323
NM_007324
ZFYVE9


zinc finger, FYVE domain containing 9


chr6_+_138188352 0.560 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr2_-_101767714 0.557 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr2_+_234263141 0.557 NM_152879
DGKD
diacylglycerol kinase, delta 130kDa
chr19_+_10828763 0.556 DNM2
dynamin 2
chr5_+_179248089 0.551 SQSTM1
sequestosome 1
chr11_-_118781612 0.549 NM_182557
BCL9L
B-cell CLL/lymphoma 9-like
chr15_-_101835360 0.548 SNRPA1
small nuclear ribonucleoprotein polypeptide A'
chr18_-_45935627 0.546 ZBTB7C
zinc finger and BTB domain containing 7C
chr1_+_1567556 0.546 NM_006983
MMP23B
matrix metallopeptidase 23B
chr16_-_57318452 0.545 PLLP
plasmolipin
chr1_-_224033383 0.544 TP53BP2
tumor protein p53 binding protein, 2
chr8_+_86089618 0.543 NM_001083588
NM_001951
E2F5

E2F transcription factor 5, p130-binding

chr5_-_141257943 0.542 NM_002587
NM_032420
PCDH1

protocadherin 1

chr1_-_205290756 0.540 NM_030952
NUAK2
NUAK family, SNF1-like kinase, 2
chr19_-_1863546 0.538 NM_031918
KLF16
Kruppel-like factor 16
chr8_+_37654757 0.537 GPR124
G protein-coupled receptor 124
chr19_+_42788605 0.536 NM_015125
CIC
capicua homolog (Drosophila)
chr11_-_65326129 0.532 LTBP3
latent transforming growth factor beta binding protein 3
chr20_+_36531548 0.526 VSTM2L
V-set and transmembrane domain containing 2 like
chr5_+_139027868 0.526 CXXC5
CXXC finger protein 5
chr22_+_20067732 0.525 NM_001190326
NM_022720
DGCR8

DiGeorge syndrome critical region gene 8

chr1_-_33815498 0.525 NM_004427
PHC2
polyhomeotic homolog 2 (Drosophila)
chr19_+_10828813 0.523 DNM2
dynamin 2
chr7_-_139876718 0.522 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr2_+_171572698 0.522 SP5
Sp5 transcription factor
chr15_-_55880508 0.520 PYGO1
pygopus homolog 1 (Drosophila)
chr19_-_49865638 0.520 NM_003598
TEAD2
TEA domain family member 2
chr9_-_35732389 0.520 NM_006289
TLN1
talin 1
chr2_-_197457250 0.518 NM_020760
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr1_-_33815411 0.517 PHC2
polyhomeotic homolog 2 (Drosophila)
chr9_+_82187599 0.516 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr16_+_67562704 0.513 NM_024519
NM_001193522
FAM65A

family with sequence similarity 65, member A

chr1_-_33430285 0.509 NM_001127361
NM_153341
RNF19B

ring finger protein 19B

chr19_+_10381763 0.509 ICAM1
intercellular adhesion molecule 1
chr11_+_64001974 0.509 NM_001243733
NM_003377
VEGFB

vascular endothelial growth factor B

chr8_+_142138684 0.503 NM_014957
DENND3
DENN/MADD domain containing 3
chr20_+_1875825 0.501 NM_001040023
SIRPA
signal-regulatory protein alpha
chr14_+_104605059 0.501 NM_015656
KIF26A
kinesin family member 26A
chr8_-_10587942 0.500 NM_031439
SOX7
SRY (sex determining region Y)-box 7
chr9_+_116917716 0.499 COL27A1
collagen, type XXVII, alpha 1
chr1_+_100818052 0.499 CDC14A
CDC14 cell division cycle 14 homolog A (S. cerevisiae)
chr12_+_7037385 0.497 NM_001940
ATN1
atrophin 1
chr18_+_77160243 0.497 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr3_-_129035069 0.496 NM_006026
H1FX
H1 histone family, member X
chr6_+_36646489 0.496 CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr11_+_369723 0.492 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr15_-_64338519 0.491 NM_014326
DAPK2
death-associated protein kinase 2
chr1_-_6545521 0.491 PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr7_+_6144504 0.490 NM_032172
USP42
ubiquitin specific peptidase 42
chr3_+_49027281 0.489 NM_177938
NM_177939
P4HTM

prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)

chr5_+_179247911 0.489 SQSTM1
sequestosome 1
chr10_-_3827418 0.483 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr19_+_49376488 0.480 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr17_+_40913211 0.478 NM_005854
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr22_+_50354139 0.478 NM_001001852
PIM3
pim-3 oncogene
chr21_+_34775740 0.476 IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr17_-_77813049 0.476 NM_003655
CBX4
chromobox homolog 4
chr22_+_33197744 0.474 TIMP3
TIMP metallopeptidase inhibitor 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 3.08e-25 GO:0009987 cellular process
1.13 6.22e-19 GO:0044237 cellular metabolic process
1.19 1.05e-18 GO:0071840 cellular component organization or biogenesis
1.16 6.82e-18 GO:0044260 cellular macromolecule metabolic process
1.19 1.62e-17 GO:0016043 cellular component organization
1.21 4.62e-16 GO:0071841 cellular component organization or biogenesis at cellular level
1.20 1.32e-14 GO:0071842 cellular component organization at cellular level
1.11 9.74e-14 GO:0044238 primary metabolic process
1.10 4.11e-13 GO:0008152 metabolic process
1.13 1.97e-12 GO:0043170 macromolecule metabolic process
1.24 1.49e-11 GO:0006996 organelle organization
1.18 1.21e-10 GO:0044267 cellular protein metabolic process
1.08 4.31e-08 GO:0050789 regulation of biological process
1.19 5.59e-08 GO:0006464 protein modification process
1.07 1.20e-07 GO:0065007 biological regulation
1.18 2.95e-07 GO:0043412 macromolecule modification
1.22 5.26e-07 GO:0051641 cellular localization
1.08 5.63e-07 GO:0050794 regulation of cellular process
1.14 9.41e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14 1.18e-06 GO:0019538 protein metabolic process
1.23 1.83e-06 GO:0051649 establishment of localization in cell
1.35 2.69e-06 GO:0007010 cytoskeleton organization
1.12 3.74e-06 GO:0051179 localization
1.15 3.94e-06 GO:0044249 cellular biosynthetic process
1.15 1.51e-05 GO:0048523 negative regulation of cellular process
1.14 1.65e-05 GO:0009058 biosynthetic process
1.12 1.75e-05 GO:0034641 cellular nitrogen compound metabolic process
1.18 3.50e-05 GO:0023051 regulation of signaling
1.21 5.40e-05 GO:0044085 cellular component biogenesis
1.17 5.99e-05 GO:0034645 cellular macromolecule biosynthetic process
1.23 6.23e-05 GO:0022008 neurogenesis
1.12 6.67e-05 GO:0051234 establishment of localization
1.12 7.41e-05 GO:0006807 nitrogen compound metabolic process
1.15 1.08e-04 GO:0048869 cellular developmental process
1.18 1.88e-04 GO:0009966 regulation of signal transduction
1.10 2.04e-04 GO:0019222 regulation of metabolic process
1.14 2.15e-04 GO:0048519 negative regulation of biological process
1.15 2.20e-04 GO:0030154 cell differentiation
1.17 2.25e-04 GO:0007399 nervous system development
1.12 2.59e-04 GO:0006810 transport
1.16 2.77e-04 GO:0009059 macromolecule biosynthetic process
1.15 3.46e-04 GO:0010467 gene expression
1.10 4.10e-04 GO:0031323 regulation of cellular metabolic process
1.33 5.94e-04 GO:0007264 small GTPase mediated signal transduction
1.35 6.22e-04 GO:0051301 cell division
1.14 7.20e-04 GO:0090304 nucleic acid metabolic process
1.22 7.31e-04 GO:0048468 cell development
1.23 8.28e-04 GO:0051128 regulation of cellular component organization
1.22 8.53e-04 GO:0048699 generation of neurons
1.30 8.93e-04 GO:0072358 cardiovascular system development
1.30 8.93e-04 GO:0072359 circulatory system development
1.17 9.95e-04 GO:0009653 anatomical structure morphogenesis
1.20 1.59e-03 GO:0007049 cell cycle
1.20 1.61e-03 GO:0006793 phosphorus metabolic process
1.20 1.61e-03 GO:0006796 phosphate metabolic process
1.10 1.87e-03 GO:0032502 developmental process
1.22 2.46e-03 GO:0046907 intracellular transport
1.39 2.52e-03 GO:0030036 actin cytoskeleton organization
1.11 2.57e-03 GO:0048518 positive regulation of biological process
1.29 2.86e-03 GO:0048646 anatomical structure formation involved in morphogenesis
1.19 3.25e-03 GO:0022607 cellular component assembly
1.15 3.25e-03 GO:0016070 RNA metabolic process
1.12 3.53e-03 GO:0048522 positive regulation of cellular process
1.10 3.66e-03 GO:0048856 anatomical structure development
1.10 5.01e-03 GO:0080090 regulation of primary metabolic process
1.23 1.12e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.09 1.45e-02 GO:0007275 multicellular organismal development
1.30 1.47e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.26 1.50e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.34 1.64e-02 GO:0030029 actin filament-based process
1.23 1.65e-02 GO:0030030 cell projection organization
1.29 2.38e-02 GO:0006886 intracellular protein transport
1.40 2.40e-02 GO:0044087 regulation of cellular component biogenesis
1.45 2.54e-02 GO:0000226 microtubule cytoskeleton organization
1.23 2.82e-02 GO:0032989 cellular component morphogenesis
1.10 2.88e-02 GO:0048731 system development
1.19 3.64e-02 GO:0016265 death
1.19 3.89e-02 GO:0008219 cell death
1.33 4.97e-02 GO:0001568 blood vessel development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 4.85e-38 GO:0005622 intracellular
1.09 2.98e-37 GO:0044424 intracellular part
1.12 2.51e-30 GO:0005737 cytoplasm
1.10 1.65e-26 GO:0043226 organelle
1.10 1.94e-26 GO:0043229 intracellular organelle
1.11 3.86e-26 GO:0043227 membrane-bounded organelle
1.11 8.57e-26 GO:0043231 intracellular membrane-bounded organelle
1.14 3.39e-22 GO:0044444 cytoplasmic part
1.22 4.09e-14 GO:0005829 cytosol
1.11 3.69e-12 GO:0044422 organelle part
1.11 4.88e-12 GO:0044446 intracellular organelle part
1.11 1.06e-11 GO:0005634 nucleus
1.03 2.27e-06 GO:0044464 cell part
1.03 2.53e-06 GO:0005623 cell
1.13 5.82e-06 GO:0043228 non-membrane-bounded organelle
1.13 5.82e-06 GO:0043232 intracellular non-membrane-bounded organelle
1.15 8.66e-06 GO:0044428 nuclear part
1.13 7.61e-05 GO:0031974 membrane-enclosed lumen
1.15 8.75e-05 GO:0031981 nuclear lumen
1.13 1.08e-04 GO:0070013 intracellular organelle lumen
1.13 1.92e-04 GO:0043233 organelle lumen
1.24 3.90e-04 GO:0015630 microtubule cytoskeleton
1.43 3.78e-03 GO:0070161 anchoring junction
1.43 7.96e-03 GO:0005912 adherens junction
1.34 9.09e-03 GO:0016323 basolateral plasma membrane
1.11 9.52e-03 GO:0031090 organelle membrane
1.13 1.07e-02 GO:0012505 endomembrane system
1.52 1.30e-02 GO:0005925 focal adhesion
1.38 1.42e-02 GO:0031252 cell leading edge
1.13 1.49e-02 GO:0005856 cytoskeleton
1.28 1.65e-02 GO:0005815 microtubule organizing center
1.27 2.01e-02 GO:0048471 perinuclear region of cytoplasm
1.49 2.15e-02 GO:0005924 cell-substrate adherens junction
1.48 2.23e-02 GO:0030055 cell-substrate junction
1.28 4.77e-02 GO:0015629 actin cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 1.04e-31 GO:0005515 protein binding
1.07 7.73e-25 GO:0005488 binding
1.19 1.44e-06 GO:0030554 adenyl nucleotide binding
1.15 1.47e-06 GO:0000166 nucleotide binding
1.16 4.06e-06 GO:0017076 purine nucleotide binding
1.18 6.30e-06 GO:0032559 adenyl ribonucleotide binding
1.25 1.56e-05 GO:0016301 kinase activity
1.16 1.58e-05 GO:0032553 ribonucleotide binding
1.16 1.58e-05 GO:0032555 purine ribonucleotide binding
1.15 3.00e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.17 3.34e-05 GO:0005524 ATP binding
1.22 4.71e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.16 6.43e-05 GO:0016740 transferase activity
1.24 6.54e-05 GO:0019899 enzyme binding
1.24 1.64e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.08 2.51e-04 GO:0003824 catalytic activity
1.30 5.14e-04 GO:0004674 protein serine/threonine kinase activity
1.24 1.03e-03 GO:0004672 protein kinase activity
1.27 1.64e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.25 1.99e-03 GO:0008092 cytoskeletal protein binding
1.27 3.16e-03 GO:0030695 GTPase regulator activity